Epigallocatechin-3-gallate (EGCG) protects against chromate-induced toxicity in vitro
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منابع مشابه
(−)-Epigallocatechin-3-gallate (EGCG), a polyphenol, protects against sepsis-induced acute liver injury in rats
Sepsis is a significant public health problem and is one of the leading causes of death in critically ill patients admitted to the intensive care unit. Liver dysfunction occurs frequently in cases of sepsis. This study aims to investigate the protective effects of (−)-epigallocatechin-3-gallate (EGCG) on polymicrobial sepsis-induced acute liver injury and to explore the underlying mechanism. Se...
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Epigallocatechin gallate (EGCG), a major polyphenol in green tea, possesses antioxidant properties and regulates various cell functions. Here, we examined the function of EGCG in inflammatory bone resorption. In calvarial organ cultures, lipopolysaccharide (LPS)-induced bone resorption was clearly suppressed by EGCG. In osteoblasts, EGCG suppressed the LPS-induced expression of COX-2 and mPGES-...
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Neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD) enforce an overwhelming social and economic burden on society. They are primarily characterized through the accumulation of modified proteins, which further trigger biological responses such as inflammation, oxidative stress, excitotoxicity and modulation of signalling pathways. In a hope for cure, these di...
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PURPOSE (-)-epigallocatechin-3-gallate (EGCG), a major catechin component of green tea, is reported to delay or prevent certain forms of cancer, arthritis, cardiovascular disease, and neurodegenerative disorders. In this study, we determined if systemically administered EGCG could protect the retina against light damage (LD) in mice. METHODS BALB/cJ mice were treated with either EGCG or salin...
متن کاملHuman hair growth enhancement in vitro by green tea epigallocatechin-3-gallate (EGCG).
Green tea is a popular worldwide beverage, and its potential beneficial effects such as anti-cancer and anti-oxidant properties are believed to be mediated by epigallocatechin-3-gallate (EGCG), a major constituent of polyphenols. Recently, it was reported that EGCG might be useful in the prevention or treatment of androgenetic alopecia by selectively inhibiting 5alpha-reductase activity. Howeve...
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ژورنال
عنوان ژورنال: Toxicology and Applied Pharmacology
سال: 2012
ISSN: 0041-008X
DOI: 10.1016/j.taap.2011.10.018